Beverly D'Angelo admits to unscripted ‘Christmas Vacation’ moment with Chevy Chase that made movie history



© Yara Nardi/Reuters

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Exclusive: Scientists find a way to forecast hypertrophic cardiomyopathy, which affects millions worldwide
Scientists are developing a simple blood test to predict who is most at risk from the world’s most common inherited heart condition.
Millions of people worldwide have hypertrophic cardiomyopathy (HCM), a disease of the heart muscle where the wall of the heart becomes thickened. It is caused by a change in one or more genes and mostly passed on through families.
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© Photograph: British Heart Foundation

© Photograph: British Heart Foundation

© Photograph: British Heart Foundation
Religious groups using banned drugs are increasingly testing the limits of faith and law – and winning
The Church of Gaia in Spokane, Washington, has all the makings of a traditional place of worship: regular gatherings, communal songs and member donations – except they also serve ayahuasca, a psychedelic substance that can induce nausea and, at times, projectile vomiting.
“This is a purely spiritual practice,” said Connor Mize, the ceremonial leader of the Church of Gaia. “It’s not a thing you do just for fun.”
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© Photograph: John Moore/Getty Images

© Photograph: John Moore/Getty Images

© Photograph: John Moore/Getty Images
The rules-based global order, its institutions and value system face a crisis of legitimacy and credibility as the US turns away
‘The old world is dying,” Antonio Gramsci once wrote. “And the new world struggles to be born.” In such interregnums, the Italian Marxist philosopher suggested, “every act, even the smallest, may acquire decisive weight”.
In 2025, western leaders appeared convinced they – and we – were living through one such transitional period, as the world of international relations established after the second world war crashed to a halt.
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© Illustration: Brian Stauffer

© Illustration: Brian Stauffer

© Illustration: Brian Stauffer
On that brilliant night at Ally Pally 21 years ago, Laura and I decided to go to Detroit on holiday. Since then there have been countless adventures: road trips, dive bars, rock camps …
Kicking-out time, January 2004, and Laura and I are sitting on the kerb waiting for a bus outside Alexandra Palace in north London. Not that we’re in a hurry to be anywhere else. We’re having the best time on our kerb, cheeks flushed from hard liquor and the exhilaration of the White Stripes show we’ve just seen. We’re busy communing with a fellow nocturnal creature, a woodlouse. It is one of those rare moments in my 20s when just about everything feels right.
Laura and I had quietly become office allies over a few years, a bond initially forming around our mutual shy diligence in the face of not fully fitting in. We would conspiratorially skip downstairs to the canteen together most lunchtimes and temper any work worries by chatting shit, laughing hysterically and plotting small acts of rebellion. (Like the time we childishly made a “FUCK CHESS” sign and left it on the office chess club’s shelf, which for some reason felt necessary and hilarious. If you’re reading this, chess club, we’re very sorry.)
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© Illustration: Mark Long/The Guardian

© Illustration: Mark Long/The Guardian

© Illustration: Mark Long/The Guardian




































Andrew Mountbatten-Windsor’s daughters seen at Sandringham church as more details about his ties to Jeffrey Epstein emerge
Princesses Eugenie and Beatrice attended church with the royal family on Christmas morning, in a year where their father, Andrew Mountbatten-Windsor, was stripped of his royal titles.
Mountbatten-Windsor’s two daughters could be seen walking behind King Charles III and Queen Camilla on their way to church on the private Sandringham estate in Norfolk.
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© Photograph: Henry Nicholls/AFP/Getty Images

© Photograph: Henry Nicholls/AFP/Getty Images

© Photograph: Henry Nicholls/AFP/Getty Images



Officers closed Christmas event in Haifa, confiscating equipment and also arresting a DJ and a street vendor
Israeli police arrested a Palestinian man dressed as Santa Claus during a raid on a Christmas party in Haifa, a civil rights monitor has said.
Israeli officers closed an event celebrating Christmas on Sunday, confiscating equipment, and arresting the Palestinian Santa Claus, as well as a DJ and a street vendor. In a video, police can be seen pushing the men to the ground and handcuffing them as bystanders watched.
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© Photograph: Ariel Schalit/AP

© Photograph: Ariel Schalit/AP

© Photograph: Ariel Schalit/AP