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Ultrasound system solves the “unsticking problem” in biomedical research

“Surround sound for biological cells,” is how Luke Cox describes the ultrasound technology that Impulsonics has developed to solve the “unsticking problem” in biomedical science. Cox is co-founder and chief executive of UK-based Impulsonics, which spun-out of the University of Bristol in 2023.

He is also my guest in this episode of the Physics World Weekly podcast. He explains why living cells tend to stick together and why this can be a barrier to scientific research and the development of new medical treatments.

The system uses an array of ultrasound transducers to focus sound so that it frees-up and manipulates cells in a way that does not alter their biological properties. This is unlike chemical unsticking processes, which can change cells and impact research results.

We also chat about Cox’s career arc from PhD student to chief executive and explore opportunities for physicists in the biomedical industry.

The following articles are mentioned in the podcast:

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Scientists are failing to disclose their use of AI despite journal mandates, finds study

An analysis of more than 5.2 million papers in 5000 different journals has revealed a dramatic rise in the use of artificial intelligence (AI) tools in academic writing across all scientific disciplines, especially physics.

However, the analysis has revealed a big gap between the number of researchers who use AI and those who admit to doing so – even though most scientific journals have policies requiring the use of AI to be disclosed.

Carried out by data scientist Yi Bu from Peking University and colleagues, the analysis looks at papers that are listed in the OpenAlex dataset and were published between 2021 and 2025.

To assess the impact of editorial guidelines introduced in response to the growing use of generative AI tools such as ChatGPT, they examined journal AI-writing policies, looked at author disclosures and used AI to see if papers had been written with the help of technology.

The AI detection analysis reveals that the use of AI writing tools has increased dramatically across all scientific disciplines since 2023. It also finds that 70% of journals have adopted AI policies, which primarily require authors to disclose the use of AI-writing tools.

IOP Publishing, which publishes Physics World, for example, has a journals policy that supports authors who use AI in a “responsible and appropriate” manner. It encourages authors, however, to be “transparent about their use of any generative AI tools in either the research or the drafting of the manuscript”.

A new framework

But in the new study, a full-text analysis of 75 000 papers published since 2023, reveals that only 76 articles (about 0.1% of the total) explicitly disclosed the use of AI writing tools.

In addition, the study finds no significant difference in the use of AI between journals that have disclosure policies and those that do not, which suggests that disclosure requirements are being ignored – what the authors call a “transparency gap”.

The study also finds that researchers from non-English-speaking countries are more likely to rely on AI writing tools than native English speakers. Increases in the use of AI writing tools are found to be particularly rapid in journals with high levels of open-access publishing.

The authors now call for a re-evaluation of ethical frameworks to foster responsible AI integration in science. They state that prohibition or disclosure requirements are insufficient to regulate AI use, with their results showing that researchers are not complying with policies.

The authors argue that instead of “opposition and resistance”, “proactive engagement and institutional innovation” is needed “to ensure AI technology truly enhances the value of science”.

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Jared Isaacman on rebuilding, Artemis and what he’s learned during his first months as NASA administrator

NASA Administrator Jared Isaacman speaks at an agency town hall Dec. 19, a day after being sworn-in as the agency’s 15th administrator at the Mary W. Jackson NASA Headquarters Building in Washington. Credit: NASA/Bill Ingalls

When Jared Isaacman was sworn in as NASA administrator Dec. 18, he hit the ground running — or, perhaps more accurately, hit the air flying. At a town hall the next day, he said he would visit all the agency’s field centers, a task he completed by late January. In some cases he showed up […]

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Mutable Tactics raises $2.1 million for AI drone coordination in satellite-denied environments

British startup Mutable Tactics has raised $2.1 million in pre-seed funding to develop AI software enabling groups of military drones to operate autonomously, even when satellite navigation and communications are disrupted.

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Return of the (space) SPAC

Former investment banker Raphael Roettgen had to abandon a space-focused special purpose acquisition company in 2022 as hype around mergers with blank-check shell companies turned radioactive. Four years later, he’s back after helping raise more than $200 million to take a private space company public. SPACs raise cash on the stock market and then use […]

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Reliable space rescue is a prerequisite for continued economic opportunity in space and we have a long way to go

Fincke

On January 15, 2026, a collective cheer coincided with relief as four astronauts from SpaceX Crew 11 were safely returned to Earth from the International Space Station (ISS). The evacuation came after a crew member experienced a medical emergency that left them in stable condition but in need of terrestrial medical care. The successful return […]

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Blue Origin’s surprise TeraWave constellation jolts LEO broadband race

Amazon Leo satellites leaving Amazon’s payload processing facility in August. With Blue Origin’s TeraWave announcement, industry insiders wonder if Amazon and Blue Origin could ultimately compete for launch spots, a notion Blue Origin dismisses. Credit: Amazon

Blue Origin, the rocket company founded by Jeff Bezos, is preparing to enter one of the most hotly contested arenas in the space industry: global broadband from low Earth orbit (LEO). In a regulatory filing that caught many in the industry off guard, Blue Origin set forth plans for a network called TeraWave comprising more […]

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The humanity of machines: the relationship between technology and our bodies

Humanity has had a complicated relationship with machines and technology for centuries. While we created these inventions to make our lives easier, and have become heavily reliant upon them, we have often feared their impact on society.

In her debut book, The Body Digital: a Brief History of Humans and Machines from Cuckoo Clocks to ChatGPT, Vanessa Chang tells the story of this symbiotic partnership, covering tools as diverse as the self-playing piano and generative AI products. The short book combines creative storytelling, an inward look at our bodies and interpersonal relationships, and a detailed history of invention. Chang – who is the director of programmes at Leonardo, the International Society for the Arts, Sciences, and Technology in California – offers us a framework for examining future worlds based on the relationship between humanity and machines.

“Technology” has no easy definition. The Body Digital therefore takes a broad approach, looking at software, machines, infrastructure and tools. Chang examines objects as mundane as the pen and as complex as the road networks that define our cities. She focuses on the interplay between machine and human: how tools have lightened our load and become embedded in our behaviour. In doing this she asks the reader: is it possible for the human body to extract itself from technology?

Each chapter of the book centres on a different part of the human anatomy – hand, voice, ear, eye, foot, body and mind – looking at the historical relationship between that body part and technology. Chang follows this thread through to the modern day and the large-scale impact these technologies have had on the development of our communities, communications and social structures. The chapters are a vehicle for Chang to present interesting pieces of history and discussions about society and culture. Her explanations are tightly knit, and the book covers huge ground in its relatively concise page count.

Chang avoids “doomerism”, remaining even-handed about our reservations towards technological advancement. She is careful in her discussion of new technology, particularly those that are often fraught in the public discourse, such as the use of generative AI in creating art, and the potential harms of facial-recognition software.

She includes genuine concerns – like biases creeping into training data for large language models – but mitigates these fears by discussing how technologies have become enmeshed in human culture through history. Our fear of some technologies has been unfounded – take, for example, the idea that the self-playing piano would supersede live piano concerts. These debates, Chang argues, have happened throughout the history of technology, and some of the same arguments from the past can easily be applied to future technology.

While this commentary is often thought-provoking, it sometimes doesn’t go as far as it might. There is relatively limited discussion throughout the book about the technological ecosystem we currently live in and how that might impact our level of optimism about the future. In particular, the topics of human labour being supplanted by machine labour, and the impacts of tech monoliths like Apple and Google, are relatively minimal.

In one example, Chang discusses the ways in which “telecommunication technologies might serve as channels into the afterlife”, allowing us to use technology to artificially recreate the voices of our loved ones after death. While the book contains a full discussion of how uncanny and alarming this type of “artistic necrophilia” might be, Chang tempers fear by pointing out that by being careful with our data, careful with our digital selves, we might be able to “mitigate the transformation of [our] voices into pure commodities”. However, the questions of who controls our data, the relationship between data and capital, and the level of control that we have over the use of our data, is somewhat limited.

Poetic technology

The difference between offering interesting ideas and overexplaining is a hard needle to thread, and one that Chang navigates successfully. One striking feature of The Body Digital is the quality of the prose. Chang has a background in fiction writing and her descriptions reflect this. An automaton is anthropomorphized as a “petite, barefoot boy” with a “cloud of brown hair”; and the humble footpath is described as “veer[ing] at a jaunty angle from the pavement, an unruly alternative to concrete”. As a consequence, her ideas are interesting and memorable, making the book readable and often moving.

Particularly impressive is Chang’s attitude to exposition, which mimics fiction’s age-old adage of “show, don’t tell”. She gives the reader enough information to learn something new in context and ask follow-up questions, without banging the reader over the head with an answer to these questions. The book mimics the same relationship between the written word and human consciousness that Chang discusses within it. The Body Digital marinates with the reader in the way any good novel might, while teaching them something new.

The result is a poetic and well-observed text, which offers the reader a different way of understanding humanity’s relationship with technology. It reminds us that we have coexisted with machines throughout the history of our species, and that they have been helpful and positively shaped the direction of our world. While she covers too much ground to gaze in any one direction for too long, the reader is likely to come away enriched and perhaps even hopeful. And, as Chang points out, we have the opportunity to shape the future of technology, by “attending to the rich, idiosyncratic intelligence of our bodies”.

  • 2025 Melville House Publishing 256pp £14.99 pb / £9.49 ebook

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