Missiles and bombs landed across Iran, hitting political and security targets in Tehran, including supreme leader’s residence

• US-Israeli attack on Iran – live updates

• US and Israel strikes on Iran – what we know so far

The US and Israel have announced the beginning of an unprecedented joint operation against Iran, beginning with a wide-ranging bombing campaign aimed at regime change.

Israeli jets and US missiles struck hundreds of targets across Iran, sending residents fleeing in panic from major urban centres. Among the targets were Iran’s supreme leader, Ayatollah Ali Khameini, and Iran’s president, Masoud Pezeshkian, as well as weapons facilities across the country.