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Merck PCSK9 Pill Results Point to Extremely Low Cholesterol Future

The drug targets the PCSK9 protein, and could give millions of people a more affordable option to reduce their heart disease risk.

© Andrew Kelly/Reuters

Merck, which first introduced statins to the world nearly 40 years ago, announced that its new pill helped reduce heart attack and stroke rates in high risk patients by 20 percent in a year.
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How the Trump Administration Is Giving Even More Tax Breaks to the Wealthy

The Treasury Department and Internal Revenue Service are issuing rules that provide hundreds of billions of dollars in tax relief to big companies and the ultrarich.

© Eric Lee for The New York Times

Congressional Republicans celebrated the signing of the One Big Beautiful Bill Act in July. The legislation provided roughly $4 trillion in tax cuts.
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Live From New York: Zohran Mamdani’s Got Jokes

New York City’s next mayor showed during the campaign that he has a sharp sense of humor. Keeping things light at City Hall could be trickier.

© Amir Hamja for The New York Times

Zohran Mamdani won attention for his affordability platform, but undergirding his message was a sense of hope, joy and humor.
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John Cleary, Wounded in Kent State Shooting, Dies at 74

He was shot in 1970 by the National Guard during a student protest over the Vietnam War that left four dead in Ohio. A photo of him lying on the ground and bleeding made the cover of Life magazine.

© Howard Ruffner/Getty Images

The Ohio National Guard opened fire on antiwar protesters at Kent State University on May 4, 1970. John Cleary, lying on the ground, was a bystander when he was shot in the chest. Four students were fatally shot and nine others were wounded during the incident.
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At Least 4 Dead After Driver Slams Into Crowd Outside a Tampa Bar, Police Say

The crash left 11 people injured. The police said they chased the vehicle after trying to pull over a reckless driver, who sped off and then lost control.

© Jefferee Woo/Tampa Bay Times, via Associated Press

The driver was earlier involved in a street race a few miles away and sped off, leading to a police chase through Tampa, Fla., before the driver lost control and crashed, officials said.
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Why Is Trump So Afraid of American Voters?

President Trump raged after Democrats won multiple elections this week. And now he’s calling on lawmakers to take action: To do more gerrymandering, to outlaw mail-in ballots and to make voter ID laws more strict. Why is Trump so afraid of American voters? He’s afraid of losing his majority in the midterm elections, argues Times Opinion editor Kathleen Kingsbury.
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A New Generation of Gamblers Searches for Help

The sports betting boom has drawn in millions of young men. Are recovery efforts for problem gamblers lagging behind?

© Rachel Woolf for The New York Times

Zach Everett realized he had a gambling problem after moving to Colorado, which had legalized sports betting apps. But he struggled for years to find a path to recovery that worked.
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Sound System

It can be challenging to discover new music on streaming platforms. Today, some ideas to help you out of a listening rut.
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Inside Trump’s Deportation of Venezuelans: Four Months in a Salvadoran Prison

The Times interviewed dozens of migrant men sent to a prison in El Salvador by the Trump administration. Independent forensic analysts called the testimony credible and consistent and said the treatment met the U.N.’s definition of torture.

In March, the U.S. government sent more than 200 Venezuelan men to a maximum-security prison in El Salvador.
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Among Mamdani’s Many Upcoming Challenges: Fixing New York City’s Schools

Zohran Mamdani, the mayor-elect, will encounter dwindling enrollment, lackluster reading scores and federal officials spoiling for a fight.

© Jeenah Moon for The New York Times

New York is home to the largest and most challenging education system in the United States, with more than 1,500 schools and a $41 billion annual operating budget that could power a small nation.
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Trump Administration Appeals to Supreme Court to Block Order to Pay Full SNAP Benefits

The temporary ruling by Justice Ketanji Brown Jackson, blocking a lower court order to fully fund the aid, added to the uncertainty around the nation’s largest anti-hunger program.

© Hiroko Masuike/The New York Times

The Supplemental Nutrition Assistance Program, also known as SNAP or food stamps, provides aid to about one in eight Americans.
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Inside China’s Quest to Defy Aging with Longevity Labs and ‘Immortality Islands’

Longevity labs, “immortality islands” and grapeseed pills are part of China’s national project to conquer aging, despite sometimes shaky science and extravagant claims.

© Qilai Shen for The New York Times

Attendees trying out a cryogenic therapy room at a longevity and anti-aging conference in Shanghai in September.
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Biden Warns of a ‘Very, Very Dark Moment’ as He Hits Out at Trump

The former president, now a far less popular figure in his party, appeared in Nebraska for an overtly political speech that slammed his successor.

© Christopher Smith for The New York Times

Former President Joseph R. Biden Jr. was presented with a ceremonial quilt by Native American tribal leaders as he appeared on Friday night at a Democratic gala in Omaha.
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